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TRNAU1AP Antibody, HRP conjugated

Datasheet
Code CSB-PA882127LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TRNAU1AP Polyclonal antibody
Uniprot No.
Q9NX07
Target Names
TRNAU1AP
Alternative Names
1110007F05Rik antibody; AA387999 antibody; FLJ20503 antibody; PRO1902 antibody; RP4 669K10.4 antibody; SECp43 antibody; tRNA selenocysteine 1-associated protein 1 antibody; tRNA selenocysteine associated protein 1 antibody; tRNA selenocysteine-associated protein 1 antibody; Trnau1ap antibody; TRSPAP1 antibody; TSAP1_HUMAN antibody; WI1 2643G14.2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human tRNA selenocysteine 1-associated protein 1 protein (33-156AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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TRNAU1AP antibodies

TRNAU1AP Proteins

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Target Background

Function
Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
Gene References into Functions
  1. Knockdown of Trnau1ap reduced cell migration and proliferation. Knockdown of Trnau1ap blocked the PI3K/Akt signaling pathway. PMID: 29758194
  2. Data confirm interactions among components of the early steps of the selenocysteine biosynthesis pathway (SEPSECS, SECP43, SEPHS1, and SEPHS2); SECP43, which interacts with SEPSECS and SEPHS1, is a globular protein that forms oligomers in vivo. PMID: 28414460
  3. our studies delineating the multiple, coordinated protein-nucleic acid interactions between SECp43 and the selenoprotein cotranslational factors. PMID: 16508009
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
RRM TRSPAP family
Database Links

HGNC: 30813

KEGG: hsa:54952

STRING: 9606.ENSP00000362936

UniGene: Hs.533626

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