TULP3 Antibody, HRP conjugated

Code CSB-PA025348LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TULP3 Polyclonal antibody
Uniprot No.
Target Names
TULP3
Alternative Names
MGC45295 antibody; Tubby like protein 3 antibody; Tubby related protein 3 antibody; Tubby-like protein 3 antibody; Tubby-related protein 3 antibody; TUBL 3 antibody; TUBL3 antibody; TULP 3 antibody; TULP3 antibody; TULP3_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Tubby-related protein 3 protein (1-260AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis. During adipogenesis, regulates ciliary trafficking of FFAR4 in preadipocytes.
Gene References into Functions
  1. Data demonstrated that pancreatic cancer patients exhibiting high transcriptional levels of TULP3 showed a poor overall survival rate. PMID: 24668219
Subcellular Location
Nucleus. Cell membrane. Cell projection, cilium. Cytoplasm. Secreted.
Protein Families
TUB family
Tissue Specificity
Expressed at high levels in testis, ovaries, thyroid, and spinal chord.
Database Links

HGNC: 12425

OMIM: 604730

KEGG: hsa:7289

STRING: 9606.ENSP00000380321

UniGene: Hs.655333

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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