TXNL1 Antibody

Datasheet

Code	CSB-PA025384HA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA025384HA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA025384HA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) TXNL1 Polyclonal antibody

Uniprot No.

O43396

Target Names

TXNL1

Alternative Names

32 kDa thioredoxin related protein antibody; 32 kDa thioredoxin-related protein antibody; Thioredoxin like 1 antibody; Thioredoxin like 32kD antibody; Thioredoxin like 32kDa antibody; Thioredoxin like protein 1 antibody; Thioredoxin related 32 kDa protein antibody; Thioredoxin-like protein 1 antibody; TRP 32 antibody; TRP32 antibody; TRxL antibody; TXL 1 antibody; TXL antibody; TXL1 antibody; TXN L1 antibody; TXNL 1 antibody; TXNL antibody; Txnl1 antibody; TXNL1_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Thioredoxin-like protein 1 protein (2-289AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The TXNL1 Antibody (Product code: CSB-PA025384HA01HU) is Non-conjugated. For TXNL1 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA025384HB01HU	TXNL1 Antibody, HRP conjugated	ELISA
FITC	CSB-PA025384HC01HU	TXNL1 Antibody, FITC conjugated
Biotin	CSB-PA025384HD01HU	TXNL1 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Active thioredoxin with a redox potential of about -250 mV.

Gene References into Functions

TXNL1 is a novel regulatory molecule that inhibits cisplatin resistance in gastric cancer cells. PMID: 24525731
Distinct protein expression patterns, affecting TXNL1 and HDAC2, distinguish aneuploid with poor prognosis from diploid colorectal cancers. PMID: 21290163
Solution structure of the C-terminal DUF1000 domain of the human thioredoxin-like 1 protein. PMID: 20455272
results imply that TRP-1 is a mammalian thioredoxin and plays as a transcriptional repressor through direct binding to the transcription factor B-Myb PMID: 16231315
TXNL1 acts as an effector of oxidants or a redox sensor by converting redox changes into changes of GDI capacity to capture Rab5, which in turn modulates fluid phase endocytosis PMID: 17987124
Txnl1 is the first example of a direct connection between protein reduction and proteolysis, two major intracellular protein quality control mechanisms. PMID: 19349277
TRP32 was identified as a novel subunit of the 26 S proteasome. PMID: 19349280

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Subcellular Location

Cytoplasm. Nucleus. Note=At least 85% of the cellular TXNL1 is proteasome-associated.

Tissue Specificity

Ubiquitous.

Database Links

HGNC: 12436

OMIM: 603049

KEGG: hsa:9352

STRING: 9606.ENSP00000217515

UniGene: Hs.114412

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Service

Phage Display Service

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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