TYW5 Antibody

Code CSB-PA003860LA01HU
Size US$166
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  • Immunofluorescence staining of Hela cells with CSB-PA003860LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) TYW5 Polyclonal antibody
Uniprot No.
Target Names
TYW5
Alternative Names
TYW5 antibody; C2orf60 antibody; tRNA wybutosine-synthesizing protein 5 antibody; hTYW5 antibody; EC 1.14.11.42 antibody; tRNA(Phe antibody; 7-(3-amino-3-carboxypropyl)wyosine(37)-C(2))-hydroxylase antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human tRNA wybutosine-synthesizing protein 5 protein (1-152AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The TYW5 Antibody (Product code: CSB-PA003860LA01HU) is Non-conjugated. For TYW5 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA003860LB01HU TYW5 Antibody, HRP conjugated ELISA
FITC CSB-PA003860LC01HU TYW5 Antibody, FITC conjugated
Biotin CSB-PA003860LD01HU TYW5 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes.
Protein Families
TYW5 family
Database Links

HGNC: 26754

KEGG: hsa:129450

STRING: 9606.ENSP00000346627

UniGene: Hs.204619

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