Tbx15 Antibody, Biotin conjugated

Code CSB-PA023247LD01MO
Size US$166
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Tbx15 Polyclonal antibody
Uniprot No.
Target Names
Tbx15
Alternative Names
Tbx15 antibody; Tbx14 antibody; Tbx8 antibody; T-box transcription factor TBX15 antibody; T-box protein 15 antibody; MmTBx8 antibody; T-box transcription factor TBX14 antibody; T-box protein 14 antibody
Raised in
Rabbit
Species Reactivity
Mouse
Immunogen
Recombinant Mouse T-box transcription factor TBX15 protein (1-120AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Probable transcriptional regulator involved in the development of the skeleton of the limb, vertebral column and head. Acts by controlling the number of mesenchymal precursor cells and chondrocytes.
Gene References into Functions
  1. These studies showed that Tbx15 differentially regulates oxidative and glycolytic metabolism within subpopulations of white adipocytes and preadipocytes. PMID: 28847884
  2. Tbx15 is one of a limited number of transcription factors to be identified with a critical role in regulating glycolytic fibre identity and muscle metabolism. PMID: 26299309
  3. Tbx15 may be essential for the development of the adipogenic and thermogenic programs in adipocytes/adipomyocytes capable of developing brown adipocyte features PMID: 22912368
  4. Study establish that expression of Tbx15, Prrx1, and Pax1, among other genes involved in the specification and development of select pelvic structures, is altered in our compound mutants. PMID: 21455939
  5. Mesodermal developmental gene Tbx15 impairs adipocyte differentiation and mitochondrial respiration. PMID: 21282637
  6. phenotypes result from competition between the ectopically expressed Tbx6 and the endogenously expressed Tbx18 and Tbx15 at the binding sites of target genes PMID: 20832395
  7. Tbx15 has a role in mouse coat dorsoventral patterning PMID: 14737183
  8. Tbx15 plays an important role in the development of the skeleton of the limb, vertebral column and head by controlling the number of mesenchymal precursor cells and chondrocytes PMID: 15652702
  9. Tbx15 and Gli3 appear to have synergistic functions in formation of the scapular blade PMID: 15728667

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Subcellular Location
Nucleus.
Database Links

KEGG: mmu:21384

UniGene: Mm.88761

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