UBLCP1 Antibody, FITC conjugated

Datasheet

Code	CSB-PA851974LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) UBLCP1 Polyclonal antibody

Uniprot No.

Q8WVY7

Target Names

UBLCP1

Alternative Names

CPUB1 antibody; CTD like phosphatase domain containing protein antibody; CTD phosphatase like with ubiquitin domain 1 antibody; FLJ25267 antibody; MGC10067 antibody; Nuclear proteasome inhibitor UBLCP1 antibody; UBCP1_HUMAN antibody; Ubiquitin like domain containing CTD phosphatase 1 antibody; Ubiquitin-like domain-containing CTD phosphatase 1 antibody; UBLCP1 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Ubiquitin-like domain-containing CTD phosphatase 1 protein (2-318AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.

Gene References into Functions

Data show that UBLCP1 selectively binds to the 26S proteasome non-ATPase regulatory subunit 13 (19S regulatory particle) in regulating proteasome assembly. PMID: 28539385
the high-resolution solution structure of the UBL domain of human UBLCP1 and its interaction with Rpn1 PMID: 23667555
UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity PMID: 21949367

Subcellular Location

Nucleus. Note=Colocalizes with nuclear proteasomes.

Tissue Specificity

Broadly expressed, with highest levels in placenta, lung, testis and ovary. Up-regulated in tumor tissues.

Database Links

HGNC: 28110

OMIM: 609867

KEGG: hsa:134510

STRING: 9606.ENSP00000296786

UniGene: Hs.591733

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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