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USMG5 Antibody, FITC conjugated

Datasheet
Code CSB-PA836231LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) USMG5 Polyclonal antibody
Uniprot No.
Q96IX5
Target Names
USMG5
Alternative Names
bA792D24.4 antibody; DAPIT antibody; DKFZp566D211 antibody; HCV F-transactivated protein 2 antibody; HCVFTP2 antibody; MGC14697 antibody; Up regulated during skeletal muscle growth 5 homolog (mouse) antibody; Up-regulated during skeletal muscle growth protein 5 antibody; Usmg5 antibody; USMG5_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Up-regulated during skeletal muscle growth protein 5 protein (2-58AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. ATP5MK is a minor subunit of the mitochondrial membrane ATP synthase required for dimerization of the ATP synthase complex and as such regulates ATP synthesis in the mitochondria.
Gene References into Functions
  1. DAPIT over-expression thus appears to modulate mitochondrial functions and alter cellular regulations, promote anaerobic metabolism and induce EMT-like transition. PMID: 26161955
  2. confirm the mitochondrial presence of DAPIT on cellular level. We also show that DAPIT is localized in lysosomes of HUVEC and HEK 293T cells PMID: 22688299
  3. a critical role of DAPIT in maintaining the ATP synthase population in mitochondria and raise an intriguing possibility of active role of DAPIT in cellular energy metabolism. PMID: 21345788
Subcellular Location
Mitochondrion membrane; Single-pass membrane protein.
Database Links

HGNC: 30889

OMIM: 615204

KEGG: hsa:84833

STRING: 9606.ENSP00000311245

UniGene: Hs.500921

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