VARS2 Antibody, Biotin conjugated

Code CSB-PA735951LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) VARS2 Polyclonal antibody
Uniprot No.
Target Names
VARS2
Alternative Names
COXPD20 antibody; mitochondrial antibody; SYVM_HUMAN antibody; Valine--tRNA ligase antibody; ValRS antibody; Valyl tRNA synthetase 2 mitochondrial antibody; Valyl-tRNA synthetase antibody; Valyl-tRNA synthetase-like antibody; Vars2 antibody; VARS2L antibody; VARSL antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Valine--tRNA ligase, mitochondrial protein (830-981AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. VARS2 mutation underlies a novel autosomal recessive syndrome with epilepsy, mental retardation, short stature, growth hormone deficiency, and hypogonadism. PMID: 29137650
  2. VARS2 polymorphism significantly associated with chronic hepatitis B in Korean population. PMID: 25404243
  3. VARS2 V552V may be considered as a prognostic factor for survival in patients with early breast cancer. PMID: 20503108
  4. Data indicate that variations in the levels of VARS2L between tissue types and patients could underlie the difference in clinical presentation between individuals homoplasmic for the 1624C>T MTTV (equivalent to mt-tRNAVal C25U) mutation. PMID: 18400783
Involvement in disease
Combined oxidative phosphorylation deficiency 20 (COXPD20)
Subcellular Location
Mitochondrion.
Protein Families
Class-I aminoacyl-tRNA synthetase family
Database Links

HGNC: 21642

OMIM: 612802

KEGG: hsa:57176

STRING: 9606.ENSP00000441000

UniGene: Hs.597526

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