VARS2 Antibody, Biotin conjugated

Code CSB-PA735951LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) VARS2 Polyclonal antibody
Uniprot No.
Target Names
VARS2
Alternative Names
COXPD20 antibody; mitochondrial antibody; SYVM_HUMAN antibody; Valine--tRNA ligase antibody; ValRS antibody; Valyl tRNA synthetase 2 mitochondrial antibody; Valyl-tRNA synthetase antibody; Valyl-tRNA synthetase-like antibody; Vars2 antibody; VARS2L antibody; VARSL antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Valine--tRNA ligase, mitochondrial protein (830-981AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. VARS2 mutation underlies a novel autosomal recessive syndrome with epilepsy, mental retardation, short stature, growth hormone deficiency, and hypogonadism. PMID: 29137650
  2. VARS2 polymorphism significantly associated with chronic hepatitis B in Korean population. PMID: 25404243
  3. VARS2 V552V may be considered as a prognostic factor for survival in patients with early breast cancer. PMID: 20503108
  4. Data indicate that variations in the levels of VARS2L between tissue types and patients could underlie the difference in clinical presentation between individuals homoplasmic for the 1624C>T MTTV (equivalent to mt-tRNAVal C25U) mutation. PMID: 18400783
Involvement in disease
Combined oxidative phosphorylation deficiency 20 (COXPD20)
Subcellular Location
Mitochondrion.
Protein Families
Class-I aminoacyl-tRNA synthetase family
Database Links

HGNC: 21642

OMIM: 612802

KEGG: hsa:57176

STRING: 9606.ENSP00000441000

UniGene: Hs.597526

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