VPS51 Antibody, FITC conjugated

Code CSB-PA883424LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) VPS51 Polyclonal antibody
Uniprot No.
Target Names
VPS51
Alternative Names
ANG2 antibody; ANG3 antibody; Another new gene 2 protein antibody; C11orf3 antibody; chromosome 11 open reading frame 2 antibody; Fat free homolog antibody; ffr antibody; FFR_HUMAN antibody; FFR|FLJ13879 antibody; FLJ36472 antibody; Protein fat-free homolog antibody; Vacuolar protein sorting 51 homolog antibody; VPS51 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Vacuolar protein sorting-associated protein 51 homolog protein (595-673AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN. Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane.
Gene References into Functions
  1. A dityrosine motif of Ang2 interacts with a highly conserved groove in Syntaxin 6. PMID: 23932592
  2. Ang2 is the missing component of the Golgi-associated retrograde protein complex in most eukaryotes. PMID: 20685960
Subcellular Location
Golgi apparatus, trans-Golgi network. Recycling endosome.
Protein Families
VPS51 family
Database Links

HGNC: 1172

OMIM: 615738

KEGG: hsa:738

STRING: 9606.ENSP00000279281

UniGene: Hs.277517

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