WDFY1 Antibody, HRP conjugated

Code CSB-PA816890LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WDFY1 Polyclonal antibody
Uniprot No.
Target Names
WDFY1
Alternative Names
FENS 1 antibody; FENS-1 antibody; FENS1 antibody; KIAA1435 antibody; Phosphoinositide binding protein 1 antibody; Phosphoinositide binding protein SR1 antibody; Phosphoinositide-binding protein 1 antibody; WD repeat and FYVE domain containing 1 antibody; WD repeat and FYVE domain-containing protein 1 antibody; WD40 and FYVE domain containing protein 1 antibody; WD40- and FYVE domain-containing protein 1 antibody; WDF1 antibody; WDFY1 antibody; WDFY1_HUMAN antibody; ZFYVE17 antibody; Zinc finger FYVE domain containing protein 17 antibody; Zinc finger FYVE domain-containing protein 17 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human WD repeat and FYVE domain-containing protein 1 protein (261-357AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Positively regulates TLR3- and TLR4-mediated signaling pathways by bridging the interaction between TLR3 or TLR4 and TICAM1. Promotes TLR3/4 ligand-induced activation of transcription factors IRF3 and NF-kappa-B, as well as the production of IFN-beta and inflammatory cytokines.
Gene References into Functions
  1. NRP2 inhibits WDFY1 transcription by preventing the nuclear localization of a transcription factor, Fetal ALZ50-reactive clone 1 (FAC1). PMID: 27026195
  2. WDFY1 mediates TLR3/TLR4 signaling by recruiting TRIF. PMID: 25736436
Subcellular Location
Early endosome.
Database Links

HGNC: 20451

KEGG: hsa:57590

STRING: 9606.ENSP00000233055

UniGene: Hs.368359

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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