WDR60 Antibody

Code CSB-PA845154HA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA845154HA01HU at dilution of 1:100

  • Immunofluorescent analysis of HepG2 cells using CSB-PA845154HA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WDR60 Polyclonal antibody
Uniprot No.
Target Names
WDR60
Alternative Names
WDR60WD repeat-containing protein 60 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human WD repeat-containing protein 60 protein (1-200AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The WDR60 Antibody (Product code: CSB-PA845154HA01HU) is Non-conjugated. For WDR60 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA845154HB01HU WDR60 Antibody, HRP conjugated ELISA
FITC CSB-PA845154HC01HU WDR60 Antibody, FITC conjugated
Biotin CSB-PA845154HD01HU WDR60 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC, IF
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 2 complex (dynein-2 complex), a motor protein complex that drives the movement of cargos along microtubules within cilia and flagella in concert with the intraflagellar transport (IFT) system. DYNC2I1 plays a major role in retrograde ciliary protein trafficking in cilia and flagella. Requires also to maintain a functional transition zone.
Gene References into Functions
  1. exome analysis allowed to identify mutations not previously reported in the DYNC2H1 (MIM 603297) and WDR60 (MIM 615462) genes, both codifying for ciliary intraflagellar transport components whose mutations are known to cause Jeune syndrome PMID: 26874042
  2. These findings show that WDR60 mutations can cause skeletal ciliopathies and suggest a role for WDR60 in ciliogenesis. PMID: 23910462
Involvement in disease
Short-rib thoracic dysplasia 8 with or without polydactyly (SRTD8)
Subcellular Location
Cell projection, cilium. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.
Tissue Specificity
Expressed in chondrocytes (at protein level).
Database Links

HGNC: 21862

OMIM: 615462

KEGG: hsa:55112

STRING: 9606.ENSP00000384290

UniGene: Hs.389945

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