YY1AP1 Antibody, FITC conjugated

Code CSB-PA884488LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) YY1AP1 Polyclonal antibody
Uniprot No.
Target Names
YY1AP1
Alternative Names
FLJ10875 antibody; FLJ13914 antibody; GRNG antibody; HCCA1 antibody; HCCA2 antibody; Hepatocellular carcinoma susceptibility protein antibody; Hepatocellular carcinoma-associated protein 2 antibody; OTTHUMP00000033475 antibody; OTTHUMP00000033476 antibody; OTTHUMP00000200831 antibody; OTTHUMP00000200832 antibody; OTTHUMP00000200833 antibody; OTTHUMP00000200836 antibody; YAP antibody; YY1-associated protein 1 antibody; YY1AP antibody; YY1AP1 antibody; YYAP1_HUMAN antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human YY1-associated protein 1 protein (335-466AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation.
Gene References into Functions
  1. Data indicate WW-binding protein 2 (WBP2) as an important co-factor of YY1 associated protein 1 (YAP) that enhances YAP/TEAD-mediated gene transcription. PMID: 28332498
  2. Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease. PMID: 27939641
  3. YY1AP1 may serve as a key molecular target for EpCAM(+) AFP(+) HCC subtype PMID: 25597408
  4. human liver cancer associated gene PMID: 11856496
  5. YY1AP is a novel co-activator of YY1 PMID: 14744866
  6. HCCA2 may play a novel role in cell cycle regulation. PMID: 17541814

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Involvement in disease
Grange syndrome (GRNG)
Subcellular Location
Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus.
Tissue Specificity
Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
Database Links

HGNC: 30935

OMIM: 602531

KEGG: hsa:55249

STRING: 9606.ENSP00000357323

UniGene: Hs.584927

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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