ZBTB32 Antibody, FITC conjugated

Code CSB-PA897538LC01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZBTB32 Polyclonal antibody
Uniprot No.
Target Names
ZBTB32
Alternative Names
FANCC interacting protein antibody; FANCC-interacting protein antibody; Fanconi anemia zinc finger protein antibody; FAXF antibody; FAZF antibody; OTTHUMP00000045790 antibody; repressor of GATA antibody; Rog antibody; Testis zinc finger protein antibody; ZBT32_HUMAN antibody; Zbtb32 antibody; ZBTB32 protein antibody; Zinc finger and BTB domain containing 32 antibody; Zinc finger and BTB domain-containing protein 32 antibody; Zinc finger protein 538 antibody; ZNF538 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Zinc finger and BTB domain-containing protein 32 protein (1-294AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor. Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.
Gene References into Functions
  1. ZBTB32 is a novel negative regulator of antibody recall responses. PMID: 27357154
  2. confirmed that the promyelocytic leukemia zinc finger (PLZF) BTB dimer is strand exchanged in solution, while the FAZF BTB dimer is not PMID: 20493880
  3. Here, it was shown that human endogenous retrovirus Rec can form a trimeric complex with TZFP and AR, and can relieve the TZFP-mediated repression of AR-induced transactivation. PMID: 20147518
  4. can interact with GATA-2 and can modify GATA-2 transactivation capacity PMID: 11964310
  5. results suggest an essential role for FAZF during the proliferative stages of primitive hematopoietic progenitors, possibly acting in concert with (a subset of) the Fanconi anemia proteins PMID: 11986317
  6. TZFP is identified as a novel BMP2-induced transcription factor during osteoblastic differentiation. PMID: 17171645

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Subcellular Location
Nucleus. Note=Located in nuclear speckles.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Predominantly expressed in testis. Some isoforms are ubiquitously expressed.
Database Links

HGNC: 16763

OMIM: 605859

KEGG: hsa:27033

STRING: 9606.ENSP00000262630

UniGene: Hs.99430

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