ZFAND6 Antibody, HRP conjugated

Code CSB-PA739009HB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZFAND6 Polyclonal antibody
Uniprot No.
Target Names
ZFAND6
Alternative Names
ZFAND6 antibody; AWP1 antibody; ZA20D3 antibody; HT032 antibody; AN1-type zinc finger protein 6 antibody; Associated with PRK1 protein antibody; Zinc finger A20 domain-containing protein 3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human AN1-type zinc finger protein 6 protein (1-208AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes.
Gene References into Functions
  1. ZFAND6 was identified as a type 2 diabetes susceptibility gene. ZFAND6 plays a role in insulin secretion in vitro. PMID: 28580277
  2. By observing the data obtained from the isothermal titration calorimetry assay, both of the human proteins (KRCC1 and ZFAND6) were demonstrated to bind to their respective Toxoplasma gondii SAG1 and SAG2 proteins. PMID: 29351065
  3. The AN1 domain of AWP1 mediated the functional interaction with tumor necrosis factor receptor-associated factor 2, and the A20 domain was responsible for the negative regulation of nuclear factor kappaB activation. PMID: 21810480
Subcellular Location
Cytoplasm.
Tissue Specificity
Widely expressed with high level in heart, skeletal muscle, liver, kidney and placenta.
Database Links

HGNC: 30164

OMIM: 610183

KEGG: hsa:54469

STRING: 9606.ENSP00000261749

UniGene: Hs.596679

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