ZNF175 Antibody

Code CSB-PA026556LA01HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA026556LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF175 Polyclonal antibody
Uniprot No.
Target Names
ZNF175
Alternative Names
OTK18 antibody; Zinc finger protein 175 antibody; Zinc finger protein OTK18 antibody; ZN175_HUMAN antibody; ZNF175 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Zinc finger protein 175 protein (1-711AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ZNF175 Antibody (Product code: CSB-PA026556LA01HU) is Non-conjugated. For ZNF175 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA026556LB01HU ZNF175 Antibody, HRP conjugated ELISA
FITC CSB-PA026556LC01HU ZNF175 Antibody, FITC conjugated
Biotin CSB-PA026556LD01HU ZNF175 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Down-regulates the expression of several chemokine receptors. Interferes with HIV-1 replication by suppressing Tat-induced viral LTR promoter activity.
Gene References into Functions
  1. Transcriptional suppressor OTK18 plays a role in macrophage control of viral replication during advanced HIV-1 infection. PMID: 14688346
  2. OTK18/zinc finger protein 175 expression in brain mononuclear phagocytes is a signature for advanced HIV-1 encephalitis. PMID: 15081264
  3. Plasma OTK18 levels are positively correlated to CD8 T-cell counts, independent of HIV-1 status. PMID: 18773297
  4. These results suggest a role for OTK18 in innate immunity. PMID: 18776638
  5. These data suggest that calpain and proteasome are involved in OTK18 endoproteolysis and degradation PMID: 19034669
  6. HIV-1 induces OTK18 expression through a YIN-YANG-1 mediated manner in human macrophages PMID: 19034670
  7. OTK18 may play a role in neurotrophin production and consequently support neuronal survival. PMID: 19247725

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Subcellular Location
Cytoplasm. Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 12964

OMIM: 601139

KEGG: hsa:7728

STRING: 9606.ENSP00000262259

UniGene: Hs.119014

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