ZNF384 Antibody, FITC conjugated

Code CSB-PA03455C0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF384 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
CAG repeat protein 1 antibody; CAGH1A antibody; CAS interacting zinc finger protein antibody; CAS-interacting zinc finger protein antibody; CIZ antibody; ERDA2 antibody; GH1A antibody; NMP4 antibody; NP antibody; Nuclear matrix protein 4 antibody; Nuclear matrix transcription factor 4 antibody; TNRC1 antibody; Trinucleotide repeat containing gene 1 protei antibody; Trinucleotide repeat-containing gene 1 protein antibody; Zinc finger protein 384 antibody; ZN384_HUMAN antibody; Znf384 antibody
Raised in
Species Reactivity
Recombinant Human Zinc finger protein 384 protein (1-245AA)
Immunogen Species
Homo sapiens (Human)
Purification Method
>95%, Protein G purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1.
Gene References into Functions
  1. Ectopic expression of EP300-ZNF384 and CREBBP-ZNF384 fusion altered differentiation of mouse hematopoietic stem and progenitor cells and also potentiated oncogenic transformation in vitro.our results indicate that gene fusion is a common class of genomic abnormalities in childhood ALL and that recurrent translocations involving EP300 and CREBBP may cause epigenetic deregulation with potential for therapeutic targeting. PMID: 27903646
  2. EP300-ZNF384 mediates GATA3 gene expression and may be involved in the acquisition of the HSC gene expression signature and characteristic immunophenotype in B-cell precursor acute lymphoblastic leukemia cells. PMID: 28378055
  3. Our observations indicate that ZNF384-related fusion genes consist of a distinct subgroup of B-cell precursor acute lymphoblastic leukemia with a characteristic immunophenotype, while the clinical features depend on the functional properties of individual fusion partners. PMID: 27634205
  4. the frequency of ZNF384 gene rearrangement in pediatric precursor B cell ALL is approximately 3%. PMID: 27392123
  5. nuclear matrix protein 4 overexpression increased Aquaporin 5 mRNA expression by 2.5-fold in HEK293 cells PMID: 27058007
  6. Rare translocation t(12;17)(p13;q12), This translocation has been reported in 25 cases and its putative molecular consequence, the formation of a TAF15-ZNF384 fusion gene, in only six cases. PMID: 21504714
  7. expression in pelvic lymph nodes and primary tumors in early stage cervical carcinomas PMID: 11956602
  8. The transcription factor gene CIZ/NMP4 is recurrently involved in acute leukemia through fusion with either EWSR1 or TAF15. PMID: 12359745
  9. The CIZ protein(also known as ZNF384)was involved and rearrangemented in acute leukemia. PMID: 15990865
  10. These results suggest that caspase-mediated degradation may represent a novel regulatory mechanism that controls TAF15 and TAF15-CIZ/NMP4 activities. PMID: 19426707

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Subcellular Location
Protein Families
Krueppel C2H2-type zinc-finger protein family
Database Links

HGNC: 11955

OMIM: 609951

KEGG: hsa:171017

STRING: 9606.ENSP00000354592

UniGene: Hs.103315

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