ZNF582 Antibody, HRP conjugated

Code CSB-PA026864LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZNF582 Polyclonal antibody
Uniprot No.
Target Names
ZNF582
Alternative Names
Zinc finger protein 582 antibody; ZN582_HUMAN antibody; ZNF 582 antibody; ZNF582 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Zinc finger protein 582 protein (1-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
May be involved in transcriptional regulation.
Gene References into Functions
  1. Hypermethylated ZNF582 and PAX1 genes in the oral scrapings collected from adjacent normal oral mucosal sites rather than cancer sites are associated with aggressive progression and poor prognosis of OSCC PMID: 29224816
  2. conclude that hypermethylated ZNF582 and PAX1 are effective biomarkers for the detection of oral dysplasia and oral cancer and for the prediction of oral cancer recurrence PMID: 27865370
  3. DNA methylation status of ZNF582 showed a relatively good sensitivity and specificity for the detection of ESOPHAGEAL SQUAMOUS CELL CARCINOMA. PMID: 28241446
  4. Results show that promoter hypermethylation of ADCY8, CDH8, and ZNF582 are correlated with high-grade squamous intraepithelial lesion. PMID: 27651839
  5. This is the first study to show that ZNF582 methylation analysis of cervical swabs may be a promising choice in the positive triage of cytological diagnoses of low-grade squamous intraepithelial lesions PMID: 25134998
  6. Methylation levels of ZNF582 in uterine cervix adenocarcinomas is significantly higher than those in normal cervical tissues. PMID: 24407576
  7. ZNF582 is frequently methylated in cervical intraepithelial neoplasia 3 and worse lesions PMID: 22815913

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Subcellular Location
Nucleus.
Protein Families
Krueppel C2H2-type zinc-finger protein family
Database Links

HGNC: 26421

OMIM: 615600

KEGG: hsa:147948

STRING: 9606.ENSP00000301310

UniGene: Hs.244391

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