ZRSR2 Antibody

Code CSB-PA618014LA01HU
Size US$166
Order now
Image
  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA618014LA01HU at dilution of 1:100
The Latest Promotion Free Antibody trial simple
Have Questions? Leave a Message or Start an on-line Chat

Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ZRSR2 Polyclonal antibody
Uniprot No.
Target Names
ZRSR2
Alternative Names
CCCH type zinc finger antibody; CCCH type zinc finger; RNA binding motif and serine/arginine rich protein 2 antibody; MGC142014 antibody; MGC142040 antibody; Renal carcinoma antigen NY REN 20 antibody; Renal carcinoma antigen NY-REN-20 antibody; RNA-binding motif and serine/arginine rich protein 2 antibody; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit related protein 2 antibody; U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1 like 2 antibody; U2(RNU2) small nuclear RNA auxiliary factor 1-like 2 antibody; U2AF1 RS2 antibody; U2AF1L2 antibody; U2AF1RS2 antibody; U2AF35-related protein antibody; U2AFM_HUMAN antibody; URP antibody; Zinc finger-; CCCH domain-; and RNA-binding motif-containing serine/arginine-rich protein 2 antibody; Zrsr2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2 protein (191-372AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ZRSR2 Antibody (Product code: CSB-PA618014LA01HU) is Non-conjugated. For ZRSR2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA618014LB01HU ZRSR2 Antibody, HRP conjugated ELISA
FITC CSB-PA618014LC01HU ZRSR2 Antibody, FITC conjugated
Biotin CSB-PA618014LD01HU ZRSR2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Description

The product CSB-PA618014LA01HU is a polyclonal antibody raised in the rabbit with a peptide covering amino acids 191-372 of the human ZRSR2 protein immunized. The ZRSR2 antibody exists as an unconjugated IgG. It can specifically bind to the ZRSR2 protein, a splicing factor involved in the recognition of 3′-intron splice sites during the early stages of spliceosome assembly. This anti-ZRSR2 antibody has undergone quality tested for use in common research applications, including ELISA, WB, IHC, and IF. Its purity is over 95% using protein G purified. And it is reactive with human and mouse samples.

Customer Reviews and Q&A

 Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function
Pre-mRNA-binding protein required for splicing of both U2- and U12-type introns. Selectively interacts with the 3'-splice site of U2- and U12-type pre-mRNAs and promotes different steps in U2 and U12 intron splicing. Recruited to U12 pre-mRNAs in an ATP-dependent manner and is required for assembly of the prespliceosome, a precursor to other spliceosomal complexes. For U2-type introns, it is selectively and specifically required for the second step of splicing.
Gene References into Functions
  1. We conclude that the common clinical features of patients with an isolated mutation of ZRSR2 are a macrocytic anemia without leukopenia, thrombocytopenia or an increase in marrow blast percentage PMID: 28942350
  2. ZRSR2 has a role in RNA splicing; dysregulated splicing of U12-type introns is a characteristic feature of ZRSR2 mutations in myelodysplastic syndrome PMID: 25586593
  3. Data show that through recognition of a common splicing element, Urp facilitates distinct steps of U2- and U12-type intron splicing. PMID: 21041408
Subcellular Location
Nucleus.
Tissue Specificity
Widely expressed.
Database Links

HGNC: 23019

OMIM: 300028

KEGG: hsa:8233

STRING: 9606.ENSP00000303015

UniGene: Hs.171909

icon of phone
Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
icon of address
Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
icon of social media
Join us with

Subscribe newsletter

Leave a message

* To protect against spam, please pass the CAPTCHA test below.
CAPTCHA verification
© 2007-2024 CUSABIO TECHNOLOGY LLC All rights reserved. 鄂ICP备15011166号-1
Place an order now

I. Product details

*
*
*
*

II. Contact details

*
*

III. Ship To

*
*
*
*
*
*
*

IV. Bill To

*
*
*
*
*
*
*
*