ZSWIM6 Antibody

Datasheet

Code	CSB-PA884622LA01HU
Size	US$166
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Image	Immunofluorescent analysis of HepG2 cells using CSB-PA884622LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA884622LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ZSWIM6 Polyclonal antibody

Uniprot No.

Q9HCJ5

Target Names

ZSWIM6

Alternative Names

KIAA1577 antibody; Zinc finger SWIM domain-containing protein 6 antibody; Zswim6 antibody; ZSWM6_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Zinc finger SWIM domain-containing protein 6 protein (430-583AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The ZSWIM6 Antibody (Product code: CSB-PA884622LA01HU) is Non-conjugated. For ZSWIM6 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA884622LB01HU	ZSWIM6 Antibody, HRP conjugated	ELISA
FITC	CSB-PA884622LC01HU	ZSWIM6 Antibody, FITC conjugated
Biotin	CSB-PA884622LD01HU	ZSWIM6 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC, IF

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

involved in nervous system development, important for striatal morphology and motor regulation.

Gene References into Functions

This study builds support for a key role for ZSWIM6 in neuronal development and function, in addition to its putative roles in limb and craniofacial development, and provides a striking example of different variants in the same gene leading to distinct phenotypes. PMID: 29198722
A single recurrent heterozygous missense substitution in ZSWIM6, encoding a protein of unknown function, was previously shown to underlie this disorder in four unrelated cases. Here we describe four additional individuals from three families, comprising two sporadic subjects (one of whom had no limb malformation) and a mildly affected female with a severely affected son PMID: 26706854
Exome sequencing of one trio and two unrelated probands revealed the same heterozygous variant (c.3487C>T [p. Arg1163Trp])associated with acromelic frontonasal dysostosis in a highly conserved protein domain of ZSWIM6; this variant has not been seen in the 1000 Genomes data, dbSNP, or the Exome Sequencing Project PMID: 25105228

Involvement in disease

Acromelic frontonasal dysostosis (AFND)

Database Links

HGNC: 29316

OMIM: 603671

KEGG: hsa:57688

STRING: 9606.ENSP00000252744

UniGene: Hs.744939

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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