clpS Antibody, Biotin conjugated

Code CSB-PA16649D0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Escherichia coli (strain K12) clpS Polyclonal antibody
Uniprot No.
Target Names
clpS
Alternative Names
clpS antibody; yljA antibody; b0881 antibody; JW0865ATP-dependent Clp protease adapter protein ClpS antibody
Raised in
Rabbit
Species Reactivity
Escherichia coli
Immunogen
Recombinant Escherichia coli ATP-dependent Clp protease adapter protein ClpS protein (1-105AA)
Immunogen Species
Escherichia coli (strain K12)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation.
Gene References into Functions
  1. Between the halves of the clpA pseudo-dimer is a large flexible acidic loop that becomes better ordered upon binding of the small adaptor protein, ClpS PMID: 15037248
  2. the ClpAP-specific adaptor, ClpS, is essential for degradation of N-end rule substrates by ClpAP PMID: 16467841
  3. ClpAP recognizes N-end rule substrates directly, whereas ClpS modulates this degradation pathway. PMID: 17322400
  4. ClpS is an integral and essential component of the N-end rule pathway. PMID: 19317833
  5. The data suggest that ClpS has been optimized for the binding and delivery of N-degrons containing an N-terminal Phe or Leu. PMID: 19373253
  6. ClpS selectively binds N-terminal destabilizing residues and targets them for degradation by the ClpAP complex resulting in carefully regulated proteolysis PMID: 16467841

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Protein Families
ClpS family
Database Links
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