rbm24 Antibody, HRP conjugated

Rare Species
Code CSB-PA745088LB01DIL
Size US$166
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) rbm24 Polyclonal antibody
Uniprot No.
Target Names
rbm24
Alternative Names
rbm24 antibody; RNA-binding protein 24 antibody; RNA-binding motif protein 24 antibody; RNA-binding protein SEB-4 antibody
Raised in
Rabbit
Species Reactivity
Zebrafish
Immunogen
Recombinant Zebrafish RNA-binding protein 24 protein (2-78AA)
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound. Involved in myogenic differentiation by regulating myog levels. Binds to a huge amount of mRNAs. Required for embryonic heart development, sarcomer and M-band formation in striated muscles.
Gene References into Functions
  1. Both Rbm24a and Rbm24b are also required for normal somite and craniofacial development. PMID: 25170925
  2. Rbm24 involving in the regulation of cardiac gene expression, sarcomeric assembly, and cardiac contractility. PMID: 22345307
  3. rbm24a is a key developmental cardiac genes with unequal roles in cardiovascular formation PMID: 22011202
Subcellular Location
Nucleus. Cytoplasm.
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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