rbm24 Antibody, HRP conjugated

Code CSB-PA745088LB01DIL
Size US$166
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Product Details

Full Product Name
Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) rbm24 Polyclonal antibody
Uniprot No.
Target Names
rbm24
Alternative Names
rbm24 antibody; RNA-binding protein 24 antibody; RNA-binding motif protein 24 antibody; RNA-binding protein SEB-4 antibody
Raised in
Rabbit
Species Reactivity
Zebrafish
Immunogen
Recombinant Zebrafish RNA-binding protein 24 protein (2-78AA)
Immunogen Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound. Involved in myogenic differentiation by regulating myog levels. Binds to a huge amount of mRNAs. Required for embryonic heart development, sarcomer and M-band formation in striated muscles.
Gene References into Functions
  1. Both Rbm24a and Rbm24b are also required for normal somite and craniofacial development. PMID: 25170925
  2. Rbm24 involving in the regulation of cardiac gene expression, sarcomeric assembly, and cardiac contractility. PMID: 22345307
  3. rbm24a is a key developmental cardiac genes with unequal roles in cardiovascular formation PMID: 22011202
Subcellular Location
Nucleus. Cytoplasm.
Database Links
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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