Recommended name: Abrin-cCleaved into the following 3 chains: 1. Abrin-c A chain EC= 2. 220.127.116.11Alternative name(s): rRNA N-glycosidase Linker peptide Abrin-c B chain
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
The A chain is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits by removing adenine from position 4,324 of 28S rRNA. Abrin-a is more toxic than ricin.
Ribosome-inactivating protein family, Type 2 RIP subfamily