Recombinant Danio rerio Aristaless-related homeobox protein (arx)

Code CSB-YP523630DIL
MSDS
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Source Yeast
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Code CSB-EP523630DIL
MSDS
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Source E.coli
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Code CSB-EP523630DIL-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP523630DIL
MSDS
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Source Baculovirus
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Code CSB-MP523630DIL
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
arx
Uniprot No.
Alternative Names
arxAristaless-related homeobox protein; ARX
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Expression Region
1-453
Target Protein Sequence
MSSQYDDDSR DRSECKSKSP TVLSSYCIDS ILGRRSPCKV RQLGAQSLPA PVRPDHEMTT EVTSKENSFD SDMHLPPKLR RLYGPGGKYL DSGRGFHEHL EKGERERLLD QACESLKISQ APQVSISRSK SYRENAPFSQ SDEGQSPEHM AQELVELSTL KFEEDVVKEE ACGDNSLSPK DEESLHNDGD VKDGEDSVCL SAGSDSEEGM LKRKQRRYRT TFTSYQLEEL ERAFQKTHYP DVFTREELAM RLDLTEARVQ VWFQNRRAKW RKREKAGVQA HPTGLPFPGP LAAAHPLSHY LEGGPFPPHP HPALESAWTA AAAAAAAFPG LAPPPNSSAL PPATPLGLGT FLGTAMFRHP AFIGPTFGRL FSSMGPLTSA STAAALLRQT APPVESPVQP SAALPEPPSS SSSTAADRRA SSIAALRLKA KEHSAQLTQL NILPSGTAGK EVC
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Appears to be indispensable for the central nervous system development. May have a role in the neuronal differentiation of the ganglionic eminence and ventral thalamus. May also be involved in axonal guidance in the floor plate.
Gene References into Functions
  1. arx knock-down in zebrafish does not lead to a switch of cell fate, as reported in mouse, but rather blocks the cells in their differentiation process towards alpha-cells. PMID: 23244389
  2. Arx contributes to patterning in the prethalamic region, while Isl1 is required for differentiation of prethalamic dopaminergic neurons. PMID: 22728160
  3. Although Arx is necessary for the Dlx-dependent promotion of interneuron migration, it is not required for the GABAergic cell fate commitment mediated by Dlx factors. PMID: 18923043
Subcellular Location
Nucleus.
Protein Families
Paired homeobox family, Bicoid subfamily
Tissue Specificity
Expressed in brain.
Database Links

KEGG: dre:30657

STRING: 7955.ENSDARP00000075256

UniGene: Dr.9011

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