Recombinant Danio rerio Clusterin-associated protein 1 homolog (cluap1)

Code CSB-YP801867DIL
MSDS
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Source Yeast
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Code CSB-EP801867DIL
MSDS
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Source E.coli
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Code CSB-EP801867DIL-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP801867DIL
MSDS
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Source Baculovirus
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Code CSB-MP801867DIL
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
cluap1
Uniprot No.
Alternative Names
cluap1; zgc:56115Clusterin-associated protein 1 homolog; Qilin
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Expression Region
1-427
Target Protein Sequence
MSFRDLRNFT EMMRALGYPR LISMENFRSP NFPLVAEILI WLVKRYEPQM EIPSDVDTES DRVFFIKAVA QFMATKAHVK LNLKRLYQAD GYAVKEMLKI TSILYNAMKT KENAGGDQNN DENSKFKFDL GSKIADLKLA RQLGSEITAK GAALFDLLGQ EEDLRESRTA AIARPLEITE TERAMRAAVK DVTESIQMTK DLLNNVSSDE ASLEAKIEKK KQDLERNQKR LQTLQSVRPA FMDEYEKIEE DLEKQYQTYV EKYRNLSFLE QQLDDYHRVE QERFEEAEMA MKMRQNKLKE EEKRLMRSGV ARDEDSDVDI PEDEGSDSDI DDGQQARPHH PRHTQISGRG GARFIGSMRG GDSEETEDSE IDVDDDDEDD DEDGEEDEEE NEDLDEDNDS LEGSSGKPGR TNQSLHPQIL EESDNDF
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Required for cilia biogenesis and maintenance in the kidney, the lateral line organ and eye. Appears to function within the multiple intraflagellar transport complex B (IFT-B).
Gene References into Functions
  1. Consistent with the knowledge that CLUAP1 plays an important role in cilia function and that cilia are critical to photoreceptor function, our results indicate that hypomorphic mutations in CLUAP1 can result in dysfunctional photoreceptors without systemic abnormalities. This is the first report linking mutations in CLUAP1 to human disease and establishes CLUAP1 as a candidate Leber congenital amaurosis gene PMID: 26820066
  2. We identified a novel mutation in cluap1 and determined that photoreceptor maintenance is dependent on cluap1. PMID: 24970261
Subcellular Location
Nucleus. Cell projection, cilium.
Protein Families
CLUAP1 family
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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