Recombinant Danio rerio T-box transcription factor TBX1 (tbx1)

Code CSB-YP804295DIL
MSDS
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Source Yeast
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Code CSB-EP804295DIL
MSDS
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Source E.coli
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Code CSB-EP804295DIL-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP804295DIL
MSDS
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Source Baculovirus
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Code CSB-MP804295DIL
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
tbx1
Uniprot No.
Alternative Names
tbx1; zgc:136724; T-box transcription factor TBX1; T-box protein 1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Expression Region
1-460
Target Protein Sequence
MISAISSPWL TQLSHFCDVA AFTTSSLSSL NTPGSYHLSP SPGDPYSHHE SQFEPCPAAQ HAYNYSGSNS AQAPAQGDSG TSNCSSSSSS STPNKTLVKK NPKVANINVQ LEMKALWDEF NQLGTEMIVT KAGRRMFPTF QVKIFGMDPM ADYMLLMDFL PVDDKRYRYA FHSSSWLVAG KADPATPGRV HYHPDSPAKG AQWMKQIVSF DKLKLTNNLL DDNGHIILNS MHRYQPRFHV VYVDPRKDSE KYAEENYKTF VFEETRFTAV TAYQNHRITQ LKIASNPFAK GFRDCDPEDW PRNHRPGSLQ IMSAFARTRN PMSSPPQQNG TEKEDSRREY DRDPSGNPLH SDPTHQLMSR VLSPALPVLG GLHAVPLTAG PRSPPHELRL DGHPQPPDTL HHHPYKYPAT YEHYLGAKTR PSPYPSPSIR GHGYHPHMNP TTANMYSATS APTNYDYGPR
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Probable transcriptional regulator involved in developmental processes. Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence. Is required for normal development of the pharyngeal arch arteries. Acts cell autonomously in the pharyngeal mesendoderm and influences the development of neural crest-derived cartilages secondarily.
Gene References into Functions
  1. Conservation of Tbx1 function in zebrafish second heart field biology. PMID: 23335360
  2. Tbx1 might play an essential role in the development of pharyngeal neural crest cells in zebrafish. Cardiac performance is impaired by Tbx1 knock down in zebrafish. PMID: 20529560
  3. Retinoic acid could produce an altered Tbx1 expression pattern in zebrafish embryos. PMID: 17706063
  4. This newly identified tbx1 expression pattern in cardiac regions other than the cardiac outflow tract offers a new insight into the role of the tbx1 transcription factor in cardiac development. PMID: 12972000
Subcellular Location
Nucleus.
Tissue Specificity
Expressed in the ear and mesendodermal components of pharyngeal arches.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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