Recombinant Danio rerio Thyroid hormone receptor alpha-A (thraa)

Code CSB-YP853742DIL
MSDS
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Source Yeast
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Code CSB-EP853742DIL
MSDS
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Source E.coli
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Code CSB-EP853742DIL-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP853742DIL
MSDS
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Source Baculovirus
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Code CSB-MP853742DIL
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
thraa
Uniprot No.
Alternative Names
thraa; nr1a1a; thra; thraa1; tra1; Thyroid hormone receptor alpha-A; zTRalpha-A; Nuclear receptor subfamily 1 group A member 1-A; Thyroid hormone receptor alpha-1; TRalpha-1
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Expression Region
1-427
Target Protein Sequence
MENTEQEHNL PEGDETQWPN GVKRKRKNSQ CSMNSTSDKS ISVPGYVPSY LEKDEPCVVC GDKATGYHYR CITCEGCKGF FRRTIQKNLH PSYSCKYDSC CIIDKITRNQ CQLCRFRKCI SVGMAMDLVL DDSKRVAKRR LIEENREKRK KEEIVKTLHN RPEPTVSEWE LIRMVTEAHR HTNAQGPHWK QKRKFLPEDI GQSPAPTSDN DKVDLEAFSE FTKIITPAIT RVVDFAKKLP MFSELPCEDQ IILLKGCCME IMSLRAAVRY DPESETLTLS GEMAVSREQL KNGGLGVVSD AIFDLGKSLS QFNLDDSEVA LLQAVLLMSS DRSGLTCVEK IEKCQEMYLL AFEHYINHRK HNISHFWPKL LMKVTNLRMI GACHASRFLH MKVECPTELF PPLFLEVFED QEGSTGVAAQ EDGSCLR
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
High affinity receptor for triiodothyronine. In the absence of thyroid hormone during late blastula stage development, acts as a transcriptional repressor. Whereas in the presence of thyroid hormone, can act as an activator of transcription. In addition, represses retinoic acid (RA)-signaling during blastula and gastrula stages of development.
Gene References into Functions
  1. zebrafish uses both alternative splicing and differential expression of TRalpha genes to diversify the cellular response to thyroid hormones. PMID: 17583703
Subcellular Location
Nucleus.
Protein Families
Nuclear hormone receptor family, NR1 subfamily
Tissue Specificity
After the mid-blastula transition (MBT), expressed throughout the deep cells, which give rise to the embryo proper. In adults, isoform 2 shows highest expression in the eye and liver. Expressed in adult gonads.
Database Links
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Call us
301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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