Recombinant Danio rerio Vitamin D3 receptor B (vdrb)

Code CSB-YP628235DIL
MSDS
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Source Yeast
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Code CSB-EP628235DIL
MSDS
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Source E.coli
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Code CSB-EP628235DIL-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP628235DIL
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP628235DIL
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
vdrb
Uniprot No.
Alternative Names
vdrb; nr1i1b; gb:dq017633; Vitamin D3 receptor B; VDR-B; 1,25-dihydroxyvitamin D3 receptor B; Nuclear receptor subfamily 1 group I member 1-B
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Expression Region
1-422
Target Protein Sequence
MESAVSTSTQ VPDEFDRNVP RICGVCGDKA TGFHFNAMTC EGCKGFFRRS MKRKASFTCP FNGSCTITKD NRRHCQACRL KRCLDIGMMK EFILTDEEVQ RKKELIQRRK DEEAHREAQK PRLSDEQRNI IDTLVDAHHK TYDDSYSDFS RFRPPVREGP VTRSASRAAS LHSLSDASSD SFSHSPESGD RKMNLSNLLM MYQEQGLSSS PDSKEEDGSS LSMLPHLADL VSYSIQKVIG FAKMIPGFRE LTAEDQIALL KSSAIEVIML RSNQSFSLED MSWSCGGPEF KYCVNDVTKA GHTLELLEPL VKFQVGLKKL NLHEEEHVLL MAICLLSPDR PGVQDHVRVE ALQDKVSEVL QAYIRAHHPG GRLLYAKMIQ KLADLRSLNE EHSKQYRSLS FQPEHSMQLT PLVLEVFGGQ VT
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Nuclear receptor for calcitriol, the active form of vitamin D3 which mediates the action of this vitamin on cells. Enters the nucleus upon vitamin D3 binding where it forms heterodimers with the retinoid X receptor/RXR. The VDR-RXR heterodimers bind to specific response elements on DNA and activate the transcription of vitamin D3-responsive target genes. Recruited to promoters via its interaction with BAZ1B/WSTF which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.
Gene References into Functions
  1. zebrafish embryos lacking vdrb produced fewer sensory hair cells in the ears and showed disruption of balance and motor coordination. PMID: 27526995
Subcellular Location
Nucleus. Cytoplasm.
Protein Families
Nuclear hormone receptor family
Tissue Specificity
Detected in embryo 24 to 48 hours after fertilization, and in intestinal bulb.
Database Links
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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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