Recombinant Drosophila yakuba Trithorax group protein osa (osa)

Code CSB-YP882045DMR
MSDS
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Source Yeast
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Code CSB-EP882045DMR
MSDS
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Source E.coli
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Code CSB-EP882045DMR-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP882045DMR
MSDS
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Source Baculovirus
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Code CSB-MP882045DMR
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
osa
Uniprot No.
Alternative Names
osa; eld; Trithorax group protein osa; Protein eyelid; Fragment
Species
Drosophila yakuba (Fruit fly)
Expression Region
1-324
Target Protein Sequence
YLAAADSAMA RTVALQSPCI SYLVAFIEQA EQTALGVANQ HGINYLRENP DSMGTSLDML RRAAGTLLHL AKHPDNRSLF MQQEQRLLGL VMSHILDQQV ALIISRVLYQ VSRGTGPIHS VEFRLLQQRQ QQQLRPASAE KQAASAGGSA PVKAEAASTE TSSTEAKPAP AATTAVVNDE NSNSSQQLPP AATFNDVSNS STNSNSCGTV SSNQTNXXXX NSSHSSSAIS SQSAITVTAP SAPATGATSA XXXAITSDQQ QVSKVAAAAA AAAALSNASA AAAAAAAAAA ASVGPPTSSS VSAGAAVAQP AAPPPTNAGT TTAV
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Trithorax group (trxG) protein required for embryonic segmentation, development of the notum and wing margin, and photoreceptor differentiation. Required for the activation of genes such as Antp, Ubx and Eve. Binds to DNA without specific affinity, suggesting that it is recruited to promoters by promoter-specific proteins. Essential component of the Brahma complex, a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Acts as an essential coactivator for Zeste, which recruits the whole complex to specific genes. In contrast, it acts as a corepressor for Wg target genes, possibly via an interaction with Pan and Gro. It also acts as a negative regulator for proneural achaete-scute, when it is directly recruited by Pan and Chi. Also represses E2f activation.
Subcellular Location
Nucleus.
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