Purity
Greater than 90% as determined by SDS-PAGE.
Alternative Names
ADH beta subunit; ADH1B; ADH1B_HUMAN; ADH2; Alcohol dehydrogenase 1B; alcohol dehydrogenase 2 (class I); beta polypeptide; Alcohol dehydrogenase 2; Alcohol dehydrogenase subunit beta; Aldehyde reductase; DKFZp686C06125; OTTHUMP00000220192
Species
Homo sapiens (Human)
Expression Region
2-375aa
Target Protein Sequence
STAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKSIRTVLTF
Note: The complete sequence including tag
sequence, target protein sequence and linker sequence could be provided upon request.
Protein Length
Full Length of Mature Protein
Tag Info
N-terminal 6xHis-SUMO-tagged
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that
we have in stock, however, if you have any special requirement for the format, please remark your
requirement when placing the order, we will prepare according to your demand.
Buffer
Tris-based buffer,50% glycerol
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw
cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature
and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized
form is 12 months at -20°C/-80°C.
Lead Time
3-7 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.
Description
The expression region of this recombinant Human ADH1B covers amino acids 2-375. This ADH1B protein is expected to have a theoretical molecular weight of 55.7 kDa. This ADH1B recombinant protein is manufactured in e.coli. The N-terminal 6xHis-SUMO tag was fused into the coding gene segment of ADH1B, making it easier to detect and purify the ADH1B recombinant protein in the later stages of expression and purification.
All-trans-retinol dehydrogenase [NAD(+)] ADH1B (ADH1B) is a crucial protein involved in vitamin A metabolism. One of the primary areas of research focuses on the redox role of ADH1B in vitamin A, particularly in the visual process. ADH1B plays a crucial role in generating retinol, which is the active form of vitamin A. The expression and regulation of ADH1B in the retina are highly regarded, as well as its role in maintaining visual function and resisting eye diseases. In addition, ADH1B is associated with some metabolism-related diseases, such as liver diseases, as it participates in the ethanol metabolism pathway, making it a hot topic in alcohol metabolism and liver health research.