Recombinant Human C-type lectin domain family 3 member A (CLEC3A)

Code CSB-YP005530HU
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Source Yeast
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Code CSB-EP005530HU
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Source E.coli
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Code CSB-EP005530HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP005530HU
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Source Baculovirus
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Code CSB-MP005530HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CLEC3A
Uniprot No.
Alternative Names
C-type (calcium dependent; carbohydrate-recognition domain) lectin; superfamilymember 1 (cartilage-derived); C-type lectin domain family 3 member A; C-type lectin superfamily member 1; Cartilage-derived C-type lectin; CLC3A_HUMAN; Clec3a; CLECSF1
Species
Homo sapiens (Human)
Expression Region
23-197
Target Protein Sequence
HTSRLKAR KHSKRRVRDK DGDLKTQIEK LWTEVNALKE IQALQTVCLR GTKVHKKCYL ASEGLKHFHE ANEDCISKGG ILVIPRNSDE INALQDYGKR SLPGVNDFWL GINDMVTEGK FVDVNGIAIS FLNWDRAQPN GGKRENCVLF SQSAQGKWSD EACRSSKRYI CEFTIPQ
Protein Length
Full Length of Mature Protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Promotes cell adhesion to laminin-332 and fibronectin.
Gene References into Functions
  1. CLEC3A binds to heparan sulfate proteoglycans on cell surface, leading to the enhancement of cell adhesion to integrin ligands on ECM; cleavage of CLEC3A by MMP-7 weakens the stable adhesion of tumor cells to the matrix PMID: 19173304
Subcellular Location
Secreted.
Tissue Specificity
Restricted to cartilage and breast. Also expressed in breast cancers.
Database Links

HGNC: 2052

OMIM: 613588

KEGG: hsa:10143

STRING: 9606.ENSP00000460682

UniGene: Hs.177936

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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