Recombinant Human Collagen alpha-1 (XXII) chain (COL22A1), partial

Code CSB-YP818785HU
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Source Yeast
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Code CSB-EP818785HU
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Source E.coli
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Code CSB-EP818785HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP818785HU
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Source Baculovirus
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Code CSB-MP818785HU
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
COL22A1
Uniprot No.
Alternative Names
COL22A1Collagen alpha-1(XXII) chain
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.
Gene References into Functions
  1. Collage XXII interacts with collagen-binding integrins via the protein motifs GLQGER and GFKGER. PMID: 24428702
  2. association between serum creatinine level and polymorphisms in the collagen type XXII alpha 1 (COL22A1) gene, on chromosome 8, and in the synaptotagmin-1 (SYT1) gene, on chromosome 12 PMID: 20222955
  3. collagen XXII is the first specific extracellular matrix protein present only at tissue junctions PMID: 15016833
Subcellular Location
Secreted, extracellular space, extracellular matrix. Cytoplasm.
Protein Families
Fibril-associated collagens with interrupted helices (FACIT) family
Tissue Specificity
Restrictive expression is observed at tissue junctions such as the myotendinous junction in skeletal and heart muscle, the articular cartilage-synovial fluid junction, or the border between the anagen hair follicle and the dermis in the skin. It is deposi
Database Links

HGNC: 22989

OMIM: 610026

KEGG: hsa:169044

STRING: 9606.ENSP00000303153

UniGene: Hs.117169

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