Recombinant Human Cytospin-B (SPECC1), partial

Code CSB-YP683620HU
MSDS
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Source Yeast
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Code CSB-EP683620HU
MSDS
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Source E.coli
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Code CSB-EP683620HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP683620HU
MSDS
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Source Baculovirus
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Code CSB-MP683620HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SPECC1
Uniprot No.
Alternative Names
Cytokinesis and spindle organization B; Cytospin B; Cytospin-B; CYTSB; CYTSB_HUMAN; FLJ36955; HCMOGT 1; HCMOGT; HCMOGT-1; NSP; NSP5; Nuclear structure protein 5; Specc1; Spectrin domain with coiled coils 1 ; Sperm antigen HCMOGT 1; Sperm antigen HCMOGT-1; Sperm antigen with calponin homology and coiled coil domains 1; Sperm antigen with calponin homology and coiled-coil domains 1; sperm antigen with calponin-like and coiled coil domains 1; Structure protein NSP5a3a ; Structure protein NSP5a3b; Structure protein NSP5b3a; Structure protein NSP5b3b
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Gene References into Functions
  1. NSP 5a3a induces apoptosis in Head and Neck cell line HN30 through p73-DAXX and TRAF2-TRADD. PMID: 22170762
  2. NSP 5a3a's novel interaction with B23 and ribonuclear protein hnRNP-L implicates NSP 5a3a in cellular processes such as ribosome biogenesis and rRNA transcription . PMID: 20237420
  3. Loss of NSP 5a3a is associated with head and neck carcinoma. PMID: 21311098
  4. PCR and fluoresecne in situ hybridization shows that HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2). PMID: 15087372
Involvement in disease
A chromosomal aberration involving CYTSB may be a cause of juvenile myelomonocytic leukemia. Translocation t(5;17)(q33;p11.2) with PDGFRB.
Subcellular Location
Nucleus.; [Isoform 3]: Membrane; Lipid-anchor.; [Isoform 4]: Membrane; Lipid-anchor.; [Isoform 5]: Membrane; Lipid-anchor.
Protein Families
Cytospin-A family
Tissue Specificity
Highly expressed in testis. Barely detectable in other tissues. Also highly expressed in some cancer cell lines.
Database Links

HGNC: 30615

OMIM: 608793

KEGG: hsa:92521

STRING: 9606.ENSP00000261503

UniGene: Hs.431045

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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