Recombinant Human D site-binding protein (DBP)

Code CSB-YP606009HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP606009HU
MSDS
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Source E.coli
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Code CSB-EP606009HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP606009HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP606009HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
DBP
Uniprot No.
Alternative Names
Albumin D box-binding protein; Albumin D-element-binding protein; D site-binding protein; DBP; DBP_HUMAN; Tax-responsive enhancer element-binding protein 302; TAXREB302; TRANSCRIPTION FACTOR DBP
Species
Homo sapiens (Human)
Expression Region
1-325
Target Protein Sequence
MARPVSDRTP APLLLGGPAG TPPGGGALLG LRSLLQGTSK PKEPASCLLK EKERKAALPA ATTPGPGLET AGPADAPAGA VVGGGSPRGR PGPVPAPGLL APLLWERTLP FGDVEYVDLD AFLLEHGLPP SPPPPGGPSP EPSPARTPAP SPGPGSCGSA SPRSSPGHAP ARAALGTASG HRAGLTSRDT PSPVDPDTVE VLMTFEPDPA DLALSSIPGH ETFDPRRHRF SEEELKPQPI MKKARKIQVP EEQKDEKYWS RRYKNNEAAK RSRDARRLKE NQISVRAAFL EKENALLRQE VVAVRQELSH YRAVLSRYQA QHGAL
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.
Gene References into Functions
  1. the expression of DBP and MAPK in epilepsy patients was upregulated, suggesting a possible pathogenetic role in IE. PMID: 25503293
Subcellular Location
Nucleus.
Protein Families
BZIP family, PAR subfamily
Tissue Specificity
Ubiquitously expressed. Expressed in the suprachiasmatic nuclei (SCN) and in most peripheral tissues, with a strong circadian rhythmicity.
Database Links

HGNC: 2697

OMIM: 124097

KEGG: hsa:1628

STRING: 9606.ENSP00000222122

UniGene: Hs.414480

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