Recombinant Human Endophilin-A2(SH3GL1)

In Stock
Code CSB-EP859949HUb0
Product Type Recombinant Protein
Size US$2466
Uniprot No. Q99961
Relevance Implicated in endocytosis. May recruit other proteins to membranes with high curvature
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity Greater than 85% as determined by SDS-PAGE.
Sequence MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQPNPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGESMKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKLKRRMREASSRPKREYKPKPREPFDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRTPSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLSYVEVLVPLPQ
Research Area Cell Biology
Source E.coli
Gene Names SH3GL1
Protein Names EEN fusion partner of MLL (Endophilin-2) (Extra eleven-nineteen leukemia fusion gene protein) (EEN) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1 CNSA1) (SH3D2B)
Expression Region 1-368aa
Tag Info N-terminal 10xHis-tagged
Mol. Weight 45.0 kDa
Protein Description Full Length
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Involvement in disease In some cases of acute leukemia, a translocation results in the formation of a KMT2A/MLL1-EEN fusion gene.
Subcellular Location Cytoplasm, Early endosome membrane, Peripheral membrane protein, Cell projection, podosome
Protein Families Endophilin family
Tissue Specificity Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus.
Database Links

HGNC: 10830

OMIM: 601768

KEGG: hsa:6455

STRING: 9606.ENSP00000269886

UniGene: Hs.490415

Pathway Endocytosis

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