Recombinant Human GTPase IMAP family member 6(GIMAP6)

Code CSB-YP744083HU
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Source Yeast
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Code CSB-EP744083HU
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Source E.coli
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Code CSB-EP744083HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP744083HU
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Source Baculovirus
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Code CSB-MP744083HU
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names GIMAP6
Uniprot No. Q6P9H5
Alternative Names GIMA6_HUMAN; Gimap6; GTPase IMAP family member 6; hIAN2; hIAN6; Human immune associated nucleotide 2; IAN-2; IAN-6; IAN6 ; Immune associated nucleotide 2 ; Immune associated nucleotide 6; Immunity associated nucleotide 6 protein ; Immunity-associated nucleotide 2 protein; Immunity-associated nucleotide 6 protein
Species Homo sapiens (Human)
Expression Region 1-292
Target Protein Sequence MEEEEYEQIP QENPPEELSQ DPVLELSGGL REKEQKTPRR LRLILMGKTG SGKSATGNSI LGRDVFESKL STRPVTKTSQ RRSREWAGKE LEVIDTPNIL SPQVSPEVAD AICQAIVLSA PGPHAVLLVT QLGRFTDEDQ QVVRRLQEVF GVGVLGHTIL VFTRKEDLAG GSLEDYVRET NNQALAWLDV TLARRHCGFN NRAQGEEQEA QLRELMEKVE AIMWENEGDY YSNKAYQYTQ QNFRLKELQE RQVSQGQGSE DVPGEESWLE GLSQIQKESE EAHRCLLGKA DL
Protein Length full length protein
Tag Info The following tags are available.
N-terminal His-tagged
Tag-Free
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting
and FAQs
Protein FAQs
Storage Condition Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

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Target Background

Gene References into Functions
  1. GIMAP6 plays a role in modulating immune function and that it does this by controlling cell death and the activation of T cells. PMID: 28381553
  2. These data,demonstrating the downregulation of the mRNA and protein expression levels of GIMAP5 and GIMAP6 in the tumor tissues and blood of patients with Hepatocellular carcinoma (HCC) , suggested the involvement of GIMAP5 and GIMAP6 in the pathogenesis of HCC, and indicate their possible use as diagnostic markers for HCC. PMID: 27667392
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20237496
Subcellular Location Cytoplasm, cytosol.
Protein Families TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily, AIG1/Toc34/Toc159-like paraseptin GTPase family, IAN subfamily
Tissue Specificity Highly expressed in spleen, lymph nodes, lung and placenta. Expressed at moderate level in thymus, kidney, heart and digestive tract. Weakly expressed in other lymphoid tissues. Detected in T-cells.
Database Links

HGNC: 21918

OMIM: 616960

KEGG: hsa:474344

STRING: 9606.ENSP00000330374

UniGene: Hs.647105

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Address
7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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