Recombinant Human HMG domain-containing protein 4 (HMGXB4)

Code CSB-YP871514HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP871514HU
MSDS
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Source E.coli
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Code CSB-EP871514HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP871514HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP871514HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
HMGXB4
Uniprot No.
Alternative Names
HMGXB4; HMG2L1; HMGBCG; HMG domain-containing protein 4; HMG box-containing protein 4; High mobility group protein 2-like 1; Protein HMGBCG
Species
Homo sapiens (Human)
Expression Region
1-601
Target Protein Sequence
MAYDDSVKKE DCFDGDHTFE DIGLAAGRSQ REKKRSYKDF LREEEEIAAQ VRNSSKKKLK DSELYFLGTD THKKKRKHSS DDYYYGDISS LESSQKKKKK SSPQSTDTAM DLLKAITSPL AAGSKPSKKT GEKSSGSSSH SESKKEHHRK KVSGSSGELP LEDGGSHKSK KMKPLYVNTE TLTLREPDGL KMKLILSPKE KGSSSVDEES FQYPSQQATV KKSSKKSARD EQGALLLGHE LQSFLKTARK KHKSSSDAHS SPGPEGCGSD ASQFAESHSA NLDLSGLEPI LVESDSSSGG ELEAGELVID DSYREIKKKK KSKKSKKKKD KEKHKEKRHS KSKRSLGLSA VPVGEVTVTS GPPPSIPYAG AAAPPLPLPG LHTDGHSEKK KKKEEKDKER ERGEKPKKKN MSAYQVFCKE YRVTIVADHP GIDFGELSKK LAEVWKQLPE KDKLIWKQKA QYLQHKQNKA EATTVKRKAS SSEGSMKVKA SSVGVLSPQK KSPPTTMLLP ASPAKAPETE PIDVAAHLQL LGESLSLIGH RLQETEGMVA VSGSLSVLLD SIICALGPLA CLTTQLPELN GCPKQVLSNT LDNIAYIMPG L
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Negatively regulates Wnt/beta-catenin signaling during development.
Gene References into Functions
  1. These results highlight a previously un-reported role of HMGXB4 in the hematopoietic system and transcriptional imbalances of HMGXB4 could contribute to the aberrant expansion of the megakaryocytic lineage in primary myelofibrosis patients PMID: 26547506
  2. the first evidence of this novel HMG2L1 molecule playing an important role in attenuating smooth muscle differentiation PMID: 20511232
  3. high-mobility group protein 2-like 1 and SNP mapping of a psychotic bipolar affective disorder linkage region on 22q12.3 PMID: 17671966
Subcellular Location
Nucleus.
Database Links

HGNC: 5003

OMIM: 604702

KEGG: hsa:10042

STRING: 9606.ENSP00000216106

UniGene: Hs.588815

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