Recombinant Human Homeobox protein DLX-6 (DLX6)

Code CSB-YP006957HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP006957HU
MSDS
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Source E.coli
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Code CSB-EP006957HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP006957HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP006957HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
DLX6
Uniprot No.
Alternative Names
Distal less homeo box 6 ; Distal less homeobox 6; Distal less homeobox gene 6a ; DLX6; DLX6_HUMAN; Homeobox protein DLX-6; MGC125282; MGC125283; MGC125284; MGC125285; OTTHUMP00000205294
Species
Homo sapiens (Human)
Expression Region
1-175
Target Protein Sequence
MSHSQHSPYL QSYHNSSAAA QTRGDDTDQQ KTTVIENGEI RFNGKGKKIR KPRTIYSSLQ LQALNHRFQQ TQYLALPERA ELAASLGLTQ TQVKIWFQNK RSKFKKLLKQ GSNPHESDPL QGSAALSPRS PALPPVWDVS ASAKGVSMPP NSYMPGYSHW YSSPHQDTMQ RPQMM
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Gene References into Functions
  1. The potential DLX6-AS1/miR-203a/MMP-2 pathway. PMID: 29145165
  2. MDA-MB-231 breast neoplasms did not express DLX6 but the resulting bone/lung metastases did. PMID: 21108812
  3. single nucleotide polymorphisms in intron 1 of the DLX6 gene and in exon 4 of the PCLO gene are not in linkage disequilibrium with autism. PMID: 12707945
  4. In mice, Dlx6 acts as an intermediary between endothelin-1 signaling and transcription of the basic helix-loop-helix transcription factor dHAND during craniofacial morphogenesis. PMID: 11711438
  5. In mice, deletion of Dlx5 and Dlx6 results in skull repatterning, including a homeotic transformation of the lower jaw into an upper jaw, and supports a model of patterning within branchial arches that relies on a nested pattern of Dlx gene expression. PMID: 12193642

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Subcellular Location
Nucleus.
Protein Families
Distal-less homeobox family
Database Links

HGNC: 2919

OMIM: 600030

KEGG: hsa:1750

STRING: 9606.ENSP00000428480

UniGene: Hs.249196

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