Recombinant Human Interleukin-1 receptor-associated kinase 1-binding protein 1 (IRAK1BP1)

Code CSB-YP719624HU
MSDS
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Source Yeast
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Code CSB-EP719624HU
MSDS
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Source E.coli
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Code CSB-EP719624HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP719624HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP719624HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
IRAK1BP1
Uniprot No.
Alternative Names
ActA binding protein 3; AIP70 ; IKBP1_HUMAN; Interleukin 1 receptor associated kinase 1 binding protein 1; Interleukin-1 receptor-associated kinase 1-binding protein 1; IRAK1-binding protein 1; IRAK1BP1; Signaling molecule that associates with Pelle-like kinase; SIMPL
Species
Homo sapiens (Human)
Expression Region
1-260
Target Protein Sequence
MSLQKTPPTR VFVELVPWAD RSRENNLASG RETLPGLRHP LSSTQAQTAT REVQVSGTSE VSAGPDRAQV VVRVSSTKEA AAEAKKSVCR RLDYITQSLQ QQGVQAENIT VTKDFRRVEN AYHMEAEVCI TFTEFGKMQN ICNFLVEKLD SSVVISPPQF YHTPGSVENL RRQACLVAVE NAWRKAQEVC NLVGQTLGKP LLIKEEETKE WEGQIDDHQS SRLSSSLTVQ QKIKSATIHA ASKVFITFEV KGKEKRKKHL
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity.
Gene References into Functions
  1. Together, these studies reveal that phosphorylation of the SIMPL protein plays a critical role in SIMPL regulation by affecting both SIMPL subcellular localization and the p65 coactivator function of SIMPL. PMID: 17079333
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
IRAK1BP1 family
Database Links

HGNC: 17368

OMIM: 615375

KEGG: hsa:134728

STRING: 9606.ENSP00000358956

UniGene: Hs.656212

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