Recombinant Human Intraflagellar transport protein 172 homolog(IFT172) ,partial

Code CSB-YP887019HU
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Source Yeast
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Code CSB-EP887019HU
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Source E.coli
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Code CSB-EP887019HU-B
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP887019HU
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Source Baculovirus
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Code CSB-MP887019HU
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Source Mammalian cell
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Product Details

Purity >85% (SDS-PAGE)
Target Names IFT172
Uniprot No. Q9UG01
Alternative Names IF172_HUMAN; ift172; Intraflagellar transport 172 homolog (Chlamydomonas); Intraflagellar transport protein 172 homolog; Osm 1; Selective LIM binding factor homolog; SLB; Wim; Wimple homolog
Species Homo sapiens (Human)
Protein Length Partial
Tag Info The following tags are available.
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form Lyophilized powder
Buffer before Lyophilization Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
and FAQs
Protein FAQs
Storage Condition Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet Please contact us to get it.

Target Data

Function Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway (By similarity).
Gene References into Functions
  1. This is the second report of IFT172 mutations in BBS patients validating IFT172 as the twentieth BBS gene (BBS20). PMID: 26763875
  2. Findings identified mutations in IFT172 that lead to a recessive form of non-syndromic retinitis pigmentosa and Bardet-Biedl syndrome and suggest that the primary IFT172 mutations alone are not sufficient to explain the wide range of phenotypes. PMID: 25168386
  3. We have identified defects in IFT172 as a cause of complex asphyxiating thoracic dystrophy and Mainzer-Saldino syndrome. PMID: 24140113
Involvement in disease Short-rib thoracic dysplasia 10 with or without polydactyly (SRTD10); Retinitis pigmentosa 71 (RP71)
Subcellular Location Cell projection, cilium
Protein Families IFT172 family
Database Links

HGNC: 30391

OMIM: 607386

KEGG: hsa:26160

STRING: 9606.ENSP00000260570

UniGene: Hs.127401

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