Recombinant Human Mucin-21 (MUC21), partial

Code CSB-EP713107HU
MSDS
Size $472
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  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Product Details

Purity
Greater than 85% as determined by SDS-PAGE.
Target Names
MUC21
Uniprot No.
Research Area
Cancer
Alternative Names
Epiglycanin
Species
Homo sapiens (Human)
Source
E.coli
Expression Region
501-566aa
Target Protein Sequence
CVRNSLSLRNTFNTAVYHPHGLNHGLGPGPGGNHGAPHRPRWSPNWFWRRPVSSIAMEMSGRNSGP
Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Mol. Weight
7.3 kDa
Protein Length
Partial
Tag Info
Tag-Free
Form
Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
13-23 business days
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet & COA
Please contact us to get it.

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Target Background

Gene References into Functions
  1. CC genotype of rs886403 in MUC21 is associated with recurrence in colorectal cancer. PMID: 27803053
  2. MUC21 is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
  3. Mucin 21/epiglycanin modulates cell adhesion PMID: 20388707
  4. Identification and expression of human epiglycanin/MUC21: a novel transmembrane mucin PMID: 17977904
  5. Observational study of gene-disease association. (HuGE Navigator) PMID: 19851445

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Subcellular Location
Cell membrane; Single-pass type I membrane protein; Extracellular side.
Tissue Specificity
Expressed in lung, large intestine, thymus, and testis. Expressed in normal and malignant bronchial epithelial cells.
Database Links

HGNC: 21661

OMIM: 616991

KEGG: hsa:394263

STRING: 9606.ENSP00000365473

UniGene: Hs.448277

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