Recombinant Human Nuclear apoptosis-inducing factor 1 (NAIF1)

Code CSB-YP715122HU
MSDS
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Source Yeast
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Code CSB-EP715122HU
MSDS
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Source E.coli
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Code CSB-EP715122HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP715122HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP715122HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
NAIF1
Uniprot No.
Alternative Names
bA379C10.2; C9orf90; chromosome 9 open reading frame 90; Naif1; NAIF1_HUMAN; Nuclear apoptosis-inducing factor 1; RP11-379C10.2
Species
Homo sapiens (Human)
Expression Region
1-327
Target Protein Sequence
MAVPAKKRKM NFSEREVEII VEELELKKHL LVNHFNAGVP LAAKSAAWHG ILRRVNAVAT CRRELPEVKK KWSDLKTEVR RKVAQVRAAV EGGEAPGPTE EDGAGGPGTG GGSGGGGPAV APVLLTPMQQ RICNLLGEAT IISLPSTTEI HPVALGPSAT AAAATVTLTQ IPTETTYHTL EEGVVEYCTA EAPPPLPPET PVDMMAQHAD TSVKPQALKS RIALNSAKLI QEQRVTNLHV KEIAQHLEQQ NDLLQMIRRS QEVQACAQER QAQAMEGTQA ALSVLIQVLR PMIKDFRRYL QSNTANPAPA SDPGQVAQNG QPDSIIQ
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Induces apoptosis.
Gene References into Functions
  1. MiR-24 acted as an oncomir, at least partially through regulation of its functional target NAIF1 in non-small cell lung cancer. PMID: 25725584
  2. NAIF1 plays a role in regulating cellular migration and invasion through the MAPK pathways and may function as a tumor suppressor in the progression of gastric carcinoma. PMID: 25432142
  3. NAIF1 is down-regulated in gastric cancer. PMID: 21286669
  4. NAIF1 (C9orf90)is a nuclear protein that induces apoptosis when overexpressed PMID: 16378748
  5. The functions of two transposon-derived human proteins: HARBI1, a domesticated transposase-derived protein, and NAIF1, which contains a trihelix motif similar to that described in the Myb-like protein, was investigated. PMID: 18339812

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Subcellular Location
Nucleus.
Protein Families
NAIF1 family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 25446

OMIM: 610673

KEGG: hsa:203245

STRING: 9606.ENSP00000362170

UniGene: Hs.373606

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