Recombinant Human Nucleoside diphosphate kinase homolog 5 (NME5)

Code CSB-YP015890HU
MSDS
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Source Yeast
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Code CSB-EP015890HU
MSDS
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Source E.coli
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Code CSB-EP015890HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP015890HU
MSDS
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Source Baculovirus
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Code CSB-MP015890HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
NME5
Uniprot No.
Alternative Names
Inhibitor of p53 induced apoptosis beta; Inhibitor of p53-induced apoptosis-beta; IPIA beta; IPIA-beta; NDK-H 5; NDK5_HUMAN; NDP kinase homolog 5; NM23 H5; nm23-H5; Nm23-M5; NM23H5; NME/NM23 family member 5; NME5; Non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase); Nonmetastatic cells 5, protein expressed in; Nonmetastatic protein 23, homolog 5; Nucleoside diphosphate kinase homolog 5; Radial spoke 23 homolog; RSPH23; Testis specific nm23 homolog; Testis-specific nm23 homolog
Species
Homo sapiens (Human)
Expression Region
1-212
Target Protein Sequence
MEISMPPPQI YVEKTLAIIK PDIVDKEEEI QDIILRSGFT IVQRRKLRLS PEQCSNFYVE KYGKMFFPNL TAYMSSGPLV AMILARHKAI SYWLELLGPN NSLVAKETHP DSLRAIYGTD DLRNALHGSN DFAAAEREIR FMFPEVIVEP IPIGQAAKDY LNLHIMPTLL EGLTELCKQK PADPLIWLAD WLLKNNPNKP KLCHHPIVEE PY
Protein Length
Full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Does not seem to have NDK kinase activity. Confers protection from cell death by Bax and alters the cellular levels of several antioxidant enzymes including Gpx5. May play a role in spermiogenesis by increasing the ability of late-stage spermatids to eliminate reactive oxygen species.
Gene References into Functions
  1. study characterized for the first time the human NME5 promoter which is controlled by Sp1 transcription factor in pancreatic cancer PMID: 22564704
  2. found that Nm23-H5 and NDP kinases A and B are differently distributed in spermatids and mature spermatozoa and could therefore be involved at various levels of sperm differentiation and function PMID: 14499630
Subcellular Location
Cell projection, cilium.
Protein Families
NDK family
Tissue Specificity
Specifically expressed in testis germinal cells.
Database Links

HGNC: 7853

OMIM: 603575

KEGG: hsa:8382

STRING: 9606.ENSP00000265191

UniGene: Hs.730856

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