Recombinant Human OCIA domain-containing protein 2 (OCIAD2)

Code CSB-YP704099HU
MSDS
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Source Yeast
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Code CSB-EP704099HU
MSDS
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Source E.coli
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Code CSB-EP704099HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP704099HU
MSDS
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Source Baculovirus
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Code CSB-MP704099HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
OCIAD2
Uniprot No.
Alternative Names
OCAD2_HUMAN; OCIA domain containing 2; OCIA domain-containing protein 2; OCIAD2; ovarian carcinoma immunoreactive antigen ; Ovarian carcinoma immunoreactive antigen like protein ; Ovarian carcinoma immunoreactive antigen-like protein
Species
Homo sapiens (Human)
Expression Region
1-154
Target Protein Sequence
MASASARGNQ DKDAHFPPPS KQSLLFCPKS KLHIHRAEIS KIMRECQEES FWKRALPFSL VSMLVTQGLV YQGYLAANSR FGSLPKVALA GLLGFGLGKV SYIGVCQSKF HFFEDQLRGA GFGPQHNRHC LLTCEECKIK HGLSEKGDSQ PSAS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Gene References into Functions
  1. Our results suggest that OCIAD2 could be a useful prognostic biomarker of lung adenocarcinoma PMID: 30320419
  2. these data indicate that reduced expression of OCIAD2 by DNA hypermethylation plays an important role in hepatocellular carcinoma tumor growth and invasion. PMID: 28911005
  3. it well explained the mechanism of TGFbeta induced OCIAD2 expression in cancer microenvironment, therefore providing an important clue for the future functional analysis of OCIAD2 in tumor pathogenesis. PMID: 24949437
  4. OCIAD2 also increased the interaction of nicastrin with C99 and stimulated APP processing via gamma-secretase activation, but did not affect Notch processing PMID: 24270855
Subcellular Location
Endosome.
Database Links

HGNC: 28685

KEGG: hsa:132299

STRING: 9606.ENSP00000423014

UniGene: Hs.95835

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