Recombinant Human Phospholipase A2, membrane associated(PLA2G2A)

Code CSB-EP018091HU
Product Type Recombinant Protein
Size US$1726
Uniprot No. P14555
Relevance Thought to participate in the regulation of the phospholipid metabolism in biombranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Storage Buffer Tris-based buffer,50% glycerol
Alias GIIC sPLA2Group IIA phospholipase A2Non-pancreatic secretory phospholipase A2 ;NPS-PLA2;Phosphatidylcholine 2-acylhydrolase 2A
Species Homo sapiens (Human)
Purity Greater than 90% as determined by SDS-PAGE.
Sequence NLVNFHRMIKLTTGKEAALSYGFYGCHCGVGGRGSPKDATDRCCVTHDCCYKRLEKRGCGTKFLSYKFSNSGSRITCAKQDSCRSQLCECDKAAATCFARNKTTYNKKYQYYSNKHCRGSTPRC
Research Area Metabolism
Source E.coli
Gene Names PLA2G2A
Expression Region 21-144aa
Tag Info N-terminal 6xHis-tagged
Mol. Weight 17.9kDa
Protein Description Full Length of Mature Protein
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides
Subcellular Location Cell membrane, Peripheral membrane protein, Secreted
Protein Families Phospholipase A2 family
Database Links

HGNC: 9031

OMIM: 172411

KEGG: hsa:5320

STRING: 9606.ENSP00000364252

UniGene: Hs.466804

Pathway Vascular smooth muscle contraction
Ras signaling pathway

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