Recombinant Human Probable tubulin polyglutamylase TTLL2 (TTLL2)

Code CSB-YP863137HU
MSDS
Size Pls inquire
Source Yeast
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Code CSB-EP863137HU
MSDS
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Source E.coli
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Code CSB-EP863137HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP863137HU
MSDS
Size Pls inquire
Source Baculovirus
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Code CSB-MP863137HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
TTLL2
Uniprot No.
Alternative Names
TTLL2; C6orf104; Probable tubulin polyglutamylase TTLL2; EC 6.-.-.-; Testis-specific protein NYD-TSPG; Tubulin--tyrosine ligase-like protein 2
Species
Homo sapiens (Human)
Expression Region
1-592
Target Protein Sequence
MRGRDLCSST QSQALGSLRT TTPAFTLNIP SEANHTEQPP AGLGARLQEA GVSIPPRRGR PTPTLEKKKK PHLMAEDEPS GALLKPLVFR VDETTPAVVQ SVLLERGWNK FDKQEQNAED WNLYWRTSSF RMTEHNSVKP WQQLNHHPGT TKLTRKDCLA KHLKHMRRMY GTSLYQFIPL TFVMPNDYTK FVAEYFQERQ MLGTKHSYWI CKPAELSRGR GILIFSDFKD FIFDDMYIVQ KYISNPLLIG RYKCDLRIYV CVTGFKPLTI YVYQEGLVRF ATEKFDLSNL QNNYAHLTNS SINKSGASYE KIKEVIGHGC KWTLSRFFSY LRSWDVDDLL LWKKIHRMVI LTILAIAPSV PFAANCFELF GFDILIDDNL KPWLLEVNYS PALTLDCSTD VLVKRKLVHD IIDLIYLNGL RNEGREASNA THGNSNIDAA KSDRGGLDAP DCLPYDSLSF TSRMYNEDDS VVEKAVSVRP EAAPASQLEG EMSGQDFHLS TREMPQSKPK LRSRHTPHKT LMPYASLFQS HSCKTKTSPC VLSDRGKAPD PQAGNFVLVF PFNEATLGAS RNGLNVKRII QELQKLMNKQ HS
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Probable tubulin polyglutamylase that generates side chains of glutamate on the gamma-carboxyl group of specific glutamate residues within the C-terminal tail of target proteins. Similar to TTLL1, may acquire enzymatic activity only in complex with other proteins as it is most likely lacking domains important for autonomous activity. Probably involved in the side-chain initiation step of the polyglutamylation reaction rather than the elongation step.
Gene References into Functions
  1. Characterization of another human tubulin tyrosine ligase-like gene family member PMID: 11054573
Protein Families
Tubulin--tyrosine ligase family
Tissue Specificity
Testis.
Database Links

HGNC: 21211

KEGG: hsa:83887

STRING: 9606.ENSP00000239587

UniGene: Hs.520554

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