Recombinant Human Ras-like protein family member 11A (RASL11A)

Code CSB-YP750972HU
MSDS
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Source Yeast
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Code CSB-EP750972HU
MSDS
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Source E.coli
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Code CSB-EP750972HU-B
MSDS
Size Pls inquire
Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP750972HU
MSDS
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Source Baculovirus
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Code CSB-MP750972HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
RASL11A
Uniprot No.
Alternative Names
Ras-like protein family member 11A; RAS-like, family 11, member A; Rasl11a; RSLBA_HUMAN
Species
Homo sapiens (Human)
Expression Region
1-242
Target Protein Sequence
MRPLSMSGHF LLAPIPESSS DYLLPKDIKL AVLGAGRVGK SAMIVRFLTK RFIGDYEPNT GKLYSRLVYV EGDQLSLQIQ DTPGGVQIQD SLPQVVDSLS KCVQWAEGFL LVYSITDYDS YLSIRPLYQH IRKVHPDSKA PVIIVGNKGD LLHARQVQTQ DGIQLANELG SLFLEISTSE NYEDVCDVFQ HLCKEVSKMH GLSGERRRAS IIPRPRSPNM QDLKRRFKQA LSPKVKAPSA LG
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
Regulator of rDNA transcription. Acts in cooperation UBF/UBTF and positively regulates RNA polymerase I transcription.
Gene References into Functions
  1. In transient transfection experiments, RasL11a enhanced the transcriptional activity of an RNA polymerase I-specific reporter controlled by the rDNA enhancer/promoter region. PMID: 20168301
  2. RASL11A is down-regulated in prostate tumors as measured by quantitative real-time PCR. This result suggests that this gene may have a tumor suppressor role in prostate cancer. PMID: 15033445
Subcellular Location
Nucleus, nucleolus.
Protein Families
Small GTPase superfamily, Ras family
Tissue Specificity
Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial c
Database Links

HGNC: 23802

OMIM: 612403

KEGG: hsa:387496

STRING: 9606.ENSP00000241463

UniGene: Hs.192131

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