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Recombinant Human Regulated endocrine-specific protein 18 (RESP18)

Recombinant Human Regulated endocrine-specific protein 18 (RESP18)

Code	CSB-YP719638HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Yeast
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Code	CSB-EP719638HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
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Code	CSB-EP719638HU-B
MSDS	MSDS Datasheet
Size	Pls inquire
Source	E.coli
Conjugate	Avi-tag Biotinylated E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code	CSB-BP719638HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Baculovirus
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Code	CSB-MP719638HU
MSDS	MSDS Datasheet
Size	Pls inquire
Source	Mammalian cell
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Product Details
Customer Reviews and Q&A
Target Background

Product Details

Purity

≥85% (SDS-PAGE)

Target Names

RESP18

Uniprot No.

Q5W5W9

Alternative Names

RESP18; Regulated endocrine-specific protein 18

Species

Homo sapiens (Human)

Expression Region

31-173

Target Protein Sequence

DTSAHDGQDQ VGVGQLWPLQ GFATPVFQHL QVVLQQIIPQ GLFWKDDITQ DAMIQKMEHA SRLHPQEPCL KDGKALFPTK TTEQEEKLQL LFPSETHSPL AKVNRDQCFT SEVVSKALKQ EVANPVKGFS GPLPTVGRNP VAD

Protein Length

Full Length of Mature Protein

Tag Info

Tag type will be determined during the manufacturing process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.

Form

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer before Lyophilization

Tris/PBS-based buffer, 6% Trehalose.

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet

Please contact us to get it.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

May play an important regulatory role in corticotrophs.

Gene References into Functions

RESP18HD is required for efficient sorting of ICA512 to secretory granules: RESP18HD is a key determinant for ICA512 granule targeting. PMID: 26836020
Over-expression of RESP18 resulted in aggravated cell death induced by dopaminergic neurotoxins. PMID: 23319378
RESP18 is a luminal protein of DCVs and its expression is regulated by exposure to glucose. PMID: 17951542

Subcellular Location

Endoplasmic reticulum. Golgi apparatus. Cytoplasmic vesicle, secretory vesicle lumen.

Protein Families

RESP18 family

Tissue Specificity

Pancreas. Found in alpha, beta and delta cells in the pancreatic islets.

Database Links

HGNC: 33762

OMIM: 612721

KEGG: hsa:389075

UniGene: Hs.290551

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