Recombinant Human Serine/threonine-protein kinase MRCK gamma (CDC42BPG), partial

Code CSB-YP715719HU
MSDS
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Source Yeast
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Code CSB-EP715719HU
MSDS
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Source E.coli
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Code CSB-EP715719HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP715719HU
MSDS
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Source Baculovirus
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Code CSB-MP715719HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
CDC42BPG
Uniprot No.
Alternative Names
CDC42BPG; DMPK2; Serine/threonine-protein kinase MRCK gamma; EC 2.7.11.1; CDC42-binding protein kinase gamma; DMPK-like gamma; Myotonic dystrophy kinase-related CDC42-binding kinase gamma; MRCK gamma; MRCKG; Myotonic dystrophy protein kinase-like gamma; Myotonic dystrophy protein kinase-like alpha
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

Customer Reviews and Q&A

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Target Background

Function
May act as a downstream effector of CDC42 in cytoskeletal reorganization. Contributes to the actomyosin contractility required for cell invasion, through the regulation of MYPT1 and thus MLC2 phosphorylation.
Gene References into Functions
  1. Findings indicate that CDC42BPG may be a susceptibility locus for hyperuricemia. PMID: 29124443
  2. CDC42BPG expression is regulated by promoter methylation and Sp1 binding. PMID: 15194684
Subcellular Location
Cytoplasm. Note=Concentrates at the leading edge of cells.
Protein Families
Protein kinase superfamily, AGC Ser/Thr protein kinase family, DMPK subfamily
Tissue Specificity
Expressed in heart and skeletal muscle.
Database Links

HGNC: 29829

OMIM: 613991

KEGG: hsa:55561

STRING: 9606.ENSP00000345133

UniGene: Hs.293590

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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