Recombinant Human Small G protein signaling modulator 1 (SGSM1), partial

Code CSB-YP021201HU
MSDS
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Source Yeast
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Code CSB-EP021201HU
MSDS
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Source E.coli
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Code CSB-EP021201HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP021201HU
MSDS
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Source Baculovirus
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Code CSB-MP021201HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SGSM1
Uniprot No.
Alternative Names
KIAA1941; RUN and TBC1 domain containing 2; RUN and TBC1 domain containing protein 2; RUN and TBC1 domain-containing protein 2; RUTBC2; Sgsm1; SGSM1_HUMAN; Small G protein signaling modulator 1; Small G protein signaling modulator 1 protein
Species
Homo sapiens (Human)
Protein Length
Partial
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Function
Interacts with numerous Rab family members, functioning as Rab effector for some, and as GTPase activator for others. Promotes GTP hydrolysis by RAB34 and RAB36. Probably functions as GTPase effector with RAB9A and RAB9B; does not stimulate GTP hydrolysis with RAB9A and RAB9B.
Gene References into Functions
  1. These data show that RUTBC2 can act as a Rab36 GAP in cells and suggest that RUTBC2 links Rab9A function to Rab36 function in the endosomal system. PMID: 22637480
  2. Identification of novel protein SGSM1 which modulate small G protein (RAP and RAB)-mediated signaling pathway. PMID: 17509819
Subcellular Location
Golgi apparatus, trans-Golgi network. Cytoplasmic vesicle membrane; Peripheral membrane protein. Cytoplasm.
Protein Families
RUTBC family
Tissue Specificity
Mainly expressed in brain, heart and testis.
Database Links

HGNC: 29410

OMIM: 611417

KEGG: hsa:129049

STRING: 9606.ENSP00000383212

UniGene: Hs.474397

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