Recombinant Human Sperm protein associated with the nucleus on the X chromosome C (SPANXC)

Code CSB-YP878921HU
MSDS
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Source Yeast
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Code CSB-EP878921HU
MSDS
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Source E.coli
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Code CSB-EP878921HU-B
MSDS
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Source E.coli
Conjugate Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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Code CSB-BP878921HU
MSDS
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Source Baculovirus
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Code CSB-MP878921HU
MSDS
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Source Mammalian cell
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Product Details

Purity
>85% (SDS-PAGE)
Target Names
SPANXC
Uniprot No.
Alternative Names
Cancer-testis-associated protein CTp11 ; Cancer/testis antigen 11.3; Cancer/testis-associated protein CTp11; CT11.3; CTP11; Nuclear associated protein SPAN Xc ; Nuclear-associated protein SPAN-Xc; SPANX family member C; SPANX family; member C; SPANX family; member C1 ; SPANX-C; SPANXC; Sperm protein associated with the nucleus on the X chromosome C; SPNXC_HUMAN
Species
Homo sapiens (Human)
Expression Region
1-97
Target Protein Sequence
MDKQSSAGGV KRSVPCESNE VNETMPETPT GDSDPQPAPK KMKTSESSTI LVVRYRRNVK RTSPEELLND HARENRINPL QMEEEEFMEI MVEIPAK
Protein Length
full length protein
Tag Info
Tag type will be determined during the manufacturing process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Form
Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
Buffer before Lyophilization
Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Troubleshooting and FAQs
Storage Condition
Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
Shelf Life
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Lead Time
Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet
Please contact us to get it.

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Target Background

Gene References into Functions
  1. High SPANXC expression is associated with breast cancer invasion. PMID: 26895102
  2. study reports the isolation of AKAP3 and CTp11 Cancer/testis antigens from hepatocellular carcinoma patient sera PMID: 22941507
  3. SPANXC was found in ejaculated spermatozoa and spermatids. PMID: 15139967
  4. genetic variability of SPANX-B & SPANX-C in a sample of Sicilian male population including patients with cutaneous melanoma; statistical significant difference for a particular class of SPANX-C gene was found comparing patients with melanoma & controls PMID: 18626316
  5. SPANX-C gene dosage analysis in Down's syndrome subjects with undescended testes PMID: 19417550

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Subcellular Location
Cytoplasm. Nucleus. Note=Associated with nuclear craters.
Protein Families
SPAN-X family
Tissue Specificity
Detected in testis, melanoma and bladder carcinoma.
Database Links

HGNC: 14331

OMIM: 300330

KEGG: hsa:64663

UniGene: Hs.334464

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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